Trusted PCOS resource
The science of PCOS weight loss is different from everything you've been told. We translate the real research — and what's actually working — into one place you can start from and come back to.
Free to read. No signup required. No program to join.
Where to start
Start with what matches your situation. Come back for the rest when you need it.
I'm new to this
"I just got diagnosed" or "I'm finally taking this seriously"
Start with why insulin resistance changes the rules, then read through in order.
Start at the beginning →I've been at this for a while
"I've tried changing how I eat and it's not enough"
Compare metformin, inositol, and eating strategies side by side to figure out what to try next.
Compare options →I want to see what's changed
"I've heard GLP-1s work — what are the real options?"
Pricing, access, and what women with PCOS actually report. A lot has changed in the last 18 months.
See current GLP-1 options →What is PCOSy
Most health information treats PCOS like a simple hormonal issue. It's not. It's a metabolic condition that changes how your body processes insulin, stores fat, and responds to diet. PCOSy exists to explain that clearly — and to point you toward what's actually been shown to help.
Evidence-informed
Grounded in current research on insulin resistance, PCOS metabolism, and the treatments that have shown real results in clinical and real-world settings.
Honest about tradeoffs
We tell you what works, what doesn't, and what depends on your situation. No overselling, no "this one thing cured my PCOS" framing.
A starting point, not a program
PCOSy helps you understand your options so you can have better conversations with your doctor and make more informed decisions for yourself.
"Most women with PCOS spend years being told to eat less and exercise more — without anyone explaining why that approach often fails when insulin resistance is the actual problem."
The reason PCOSy exists
What we cover
The three approaches with the strongest evidence and real-world results for PCOS weight loss — each with a different mechanism, different tradeoffs, and different considerations.
GLP-1 Medications
Compound semaglutide and tirzepatide from $150/mo. Pricing and access have changed dramatically. The most impactful option for many women with PCOS who have struggled with other approaches.
Read more →Metformin
A prescription insulin-sensitizer used off-label for PCOS. Commonly under-discussed by doctors. One of the most effective tools for insulin resistance — and one of the most under-prescribed.
Read more →Inositol
The most widely used supplement for PCOS insulin resistance. No prescription needed. The 40:1 ratio of Myo to D-Chiro inositol is what the evidence points to — most supplements get this wrong.
Read more →The PCOS Weight Loss Cheat Sheet
Insulin resistance · GLP-1s · Metformin · Inositol · What to eat · Honest timelines
Free guide
A plain-English breakdown of the main approaches to PCOS weight loss — what they do, what they don't, and what to expect. No program to join, nothing to buy.
Read the guide now →Takes about 10 minutes. Covers GLP-1 pricing, metformin practicals, and what to ask your doctor.
How PCOSy works
PCOSy is a reference you read when you're trying to understand your options — then take back to your doctor.
Understand your situation
Learn why PCOS weight loss works differently — insulin resistance, not just calories. The foundation everything else builds on.
Explore your options
Metformin, inositol, GLP-1s — what each one does, who it tends to help, and what to realistically expect from each.
Have a better conversation
Walk into your doctor's appointment knowing what to ask for, what to expect, and how to advocate for the treatment that fits your situation.
About PCOSy
Most PCOS content online falls into two categories: generic diet advice that ignores insulin resistance, or supplement marketing dressed up as health information. PCOSy is neither.
We built this because nobody was giving women with PCOS straight answers. We cover what actually works — including prescription medications most health sites won't touch — and we're upfront about how the site is supported.
We cover what works, including things that require a prescription. Metformin and GLP-1s are among the most effective tools for PCOS weight management. Pretending otherwise doesn't help anyone.
We're honest about what doesn't work too. Inositol doesn't work for everyone. GLP-1s have real side effects. Metformin alone rarely produces dramatic weight loss. We say all of this.
Some links on this site are affiliate links. We may earn a commission if you make a purchase. This doesn't change our recommendations — we link to products because the evidence and real-world results support them, not because we're paid to recommend them.
This is not medical advice. PCOSy is a starting point for your own research and conversations with your doctor — not a substitute for professional medical care.